Case Study: Custom Assay Development

Background:

The client identified a potential side effect of one of their compounds shortly before a board meeting. The client was concerned about monoamine oxidase metabolism of the compound, but had inadequate internal biology resources for the assay.

Problem:

• A monoamine oxidase metabolic assay was needed.
• The results were needed within a week, in time for the board meeting.

Solution:

• Apredica scientists identified an appropriate assay design.
• Control compounds were identified and used to validate the assay.
• The investigational compounds were tested.
• Results were delivered in one week from go-ahead.

Results:

No significant metabolism of the test compounds was observed.

The client was able to go to the board meeting with data to support the finding that monoamine oxidase metabolism was not a problem for this set of compounds.

Contact us to learn more about Apredica's custom assay services.