Metabolic Stability Services

Apredica offers fast turnaround on a full range of in vitro metabolic stability services including microsomal stability and Cyp profiling.

Contact us to learn more our metabolic stability service.

In Vitro Metabolic Stability Services

• Hepatocytes
• Microsomes
• Plasma
• S9 or other cellular fraction
• Tissues
• Liver
• Plasma
• Whole blood
• Brain
• Heart
• Skin
• Kidney
• Fat
• Inter-Species Comparison. Available species:
• Mouse
• Rat
• Guinea pig
• Hamster
• Rabbit
• Ferret
• Dog
• Mini-pig
• Pig

Metabolite Identification

Please see metabolite profiling and identification for details.

Metabolic Profiling

Phase I

• Cytochrome P450 (Cyp)
• Monoamine Oxidase (MAO)
• Aldehyde Oxidase (AO)
• Xanthine Oxidase (XO)
• Flavin monoxidase (FMO)

Phase II

• Glucuronidation (UGT)
• Sulfotransferase (ST)
• Glutathione Transferase (GST)
• Acetyl Transferase

Apredica's scientists have many years of drug-discovery experience and can guide you through the appropriate ADME Tox and PK studies. Apredica's state-of-the-art bioanalytical services and fast turnaround times will help you make your go/no-go decisions faster while reducing your total clinical and preclinical study costs.

Contact us to learn more about Apredica's metabolic services.