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Apredica: Early ADME Tox / ADMET Contract Research

ADME Tox Services

Apredica offers discovery-focused ADME Tox services focused on the pre-GLP phase of drug development. Our emphasis is on:

  • Quality and reproducibility of results.
  • Rapid turnaround so that results may be used to accelerate medicinal chemistry cycles.
  • Cost-efficient prioritization of ADME Tox assays. We recommend starting with assays that are the least costly and most likely to identify ADME Tox liabilities. In most cases, only the leads close to being advanced to IND-enabling GLP studies require a complete ADME Tox profile.
  • A consultative approach. Each chemical series has a unique profile of ADME Tox characteristics. Our highly experienced, specialized ADME Tox scientists will help guide you through the fastest, most cost-effective path towards IND.

Contact our client services department to learn more about how Apredica can assist with your company's preclinical ADME, Tox, and Pharmacokinetics issues.

Absorption Assays

Distribution Assays

Metabolism Assays

Excretion Assays

  • Hepatocytes Uptake and Excretion: Suspension Hepatocytes

Toxicity Assays

Apredica offers a comprehensive array of toxicity assays. Please see Predictive Toxicology for details.

In Vivo Bioanalysis

  • Discovery Bioanalytical Method Development
  • Rat and Mouse Pharmacokinetics: IV, IP, PO Dosing
  • Pre-Formulation Development

Custom Assays

Custom biochemical, ELISA, protein therapeutics, and cell-based assay development. Please inquire about your custom assay needs.