Toxicity Testing ServicesApredica provides fast turnaround for a wide variety of toxicology research for drug-discovery programs, including both in vitro and in vivo toxicology research, and product safety testing for REACH compliance. Contact us to learn more our toxicity testing services. Predictive Toxicology ServicesApredica provides a suite of predictive in vitro toxicology services in screening, primary profiling, and full profiling modes. We offer in vitro cytotoxicity testing of test articles in HepG2, NIH3T3, or HaCaT cells by Neutral Red or MTT assays, as well as High-Content Imaging. We also provide the following specialized toxicity tests, and we routinely develop customized tests for clients' specialized needs. Please inquire about custom cell lines or other in vitro toxicity assays.
Toxicology Screening3 concentrations each unless indicated. Requires 12 compounds or more.
Primary Toxicology Profile9 concentrations each unless indicated.
Full Toxicology Profile9 concentrations each unless indicated.
In Vivo Preclinical ToxicologyDetermining the liabilities and potential for gross toxicity of NCEs early in the preclinical process can save large amounts of time and money on GLP toxicology studies. Apredica offers customized preclinical discovery-phase rodent toxicity studies in both single-escalating and multiple-dosing regiments with rapid turnaround. Please inquire about your preclinical animal tox needs. Please contact us about these or any cutomized tests that you may need for your drug-discovery program. Predictive ToxicologyIn recent years tremendous advances have been made in predictive toxicology, allowing early, cost-effective prediction of human toxicity. Identifying compound toxicity as early as possible can better direct your chemistry efforts, and ultimately support improved candidate selection and clinical trial success. The Safer Medicines Trust has developed a well-done film on this subject. The trailer is below, or see the full film. |
